Aluminum Silicate Nanotube Coating of Siloxane-Poly(lactic acid)-Vaterite Composite Fibermats for Bone Regeneration
نویسندگان
چکیده
منابع مشابه
Development of Magnesium and Siloxane-Containing Vaterite and Its Composite Materials for Bone Regeneration
Development of novel biomaterials with Mg(2+), Ca(2+), and silicate ions releasability for bone regeneration is now in progress. Several inorganic ions have been reported to stimulate bone-forming cells. We featured Ca(2+), silicate, and especially, Mg(2+) ions as growth factors for osteoblasts. Various biomaterials, such as ceramic powders and organic-inorganic composites, that release the ion...
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Poly(l-lactic acid)-based films which include 60 wt % of vaterite (V) or siloxane-containing vaterite (SiV) were coated on a pure magnesium substrate, denoted by PLLA/V or PLLA/SiV, respectively, to suppress early corrosion and improve its cytocompatibility. Both coating films adhered to the Mg substrate with 2.3-2.8 MPa of tensile bonding strength. Soaking test for 7 days in α-modified minimum...
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Bone regeneration is a complex, physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodeling throughout adult life. However, there are complex clinical conditions in which bone regeneration is required in large quantity, such as for skeletal reconstruction of large bone defects created by trauma, infection, tumor resection a...
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Over the past few decades, bone related disorders have constantly increased. Among all pathological conditions, osteoporosis is one of the most common and often leads to bone fractures. This is a massive burden and it affects an estimated 3 million people only in the UK. Furthermore, as the population ages, numbers are due to increase. In this context, novel biomaterials for bone fracture regen...
متن کاملPolylactic acid-phosphate glass composite foams as scaffolds for bone tissue engineering.
Phosphate glass (PG) of the composition 0.46(CaO)-0.04(Na(2)O)-0.5(P(2)O(5)) was used as filler in poly-L-lactic acid (PLA) foams developed as degradable scaffolds for bone tissue engineering. The effect of PG on PLA was assessed both in bulk and porous composite foams. Composites with various PG content (0, 5, 10, and 20 wt %) were melt-extruded, and either compression-molded or foamed through...
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ژورنال
عنوان ژورنال: Journal of Nanomaterials
سال: 2012
ISSN: 1687-4110,1687-4129
DOI: 10.1155/2012/463768